If you love science, or you have somebody who’s been impacted by a disease, this is a career that you can choose, and it’s very rewarding, it gives back more than I put in. How do you keep your energy up? How do you maintain that same easy demeanor and get-it-done attitude? Monica, you know, there's a lot going on at Gilead-that's an understatement. I remember I was at one of our manufacturing sites and we were really pushing to get these compounds to the patients, and I was telling this supplier, I’m going to ask really unreasonable things of you for a very reasonable cause, because this could be your mother, your father, your brother, your sister.ĭefinitely, I can understand what you're saying. And in fact, I had two brother-in-laws that both passed from HIV. And right off the bat in the late 80s, we started working on HIV treatments and in the Bay Area, HIV was just a devastating disease. Well, you know, when I first interviewed at Gilead, I thought it was really exciting the passion that the founder had for the company and the belief that we were going to make a difference and have impact on patients’ lives. Do you have a personal connection? What drove you to join Gilead? Many people go to the pharmaceutical industry because they have a personal connection. And then as you start to progress into developing commercial, it opens up who you're working with as far as understanding what the patient needs are, making sure you develop the best medicine possible for them. And so, you would have direct interaction with many individuals within research. In discovery, it's really important that we're there with the scientists that are identifying targets to treat HIV or treat a type of cancer. Can you give me a sense of how your team operates, and who do you work with and for? You know, the sort of, team dynamics are really integral to what we do. And that will have to be tested-is it safe and effective in people? There's so much to figure out and really, we want it to be the optimal patient experience really, so what would be best for patients and how do we deliver that? So pharmaceutical development is really: How do you make it? How do you test it? How do you administer it? So, when a compound first comes out of research, whether a small molecule or biologic, it's really an idea. You know, PDM stands for Pharmaceutical Development and Manufacturing. So PDM, what does PDM stand for within Gilead and what does PDM do? I'm in Global Supply Chain and External Manufacturing within Pharmaceutical Development and Manufacturing. Hi, my name’s Ken Kent, and I'm the Senior Vice President of Chemical Development and Manufacturing here at Gilead Sciences. Because the impossible is not impossible. Every member of our team plays a critical and visible role in helping to discover, develop and deliver innovative therapeutics for people with life-threatening diseases. We are always looking for the next wave of passionate people interested in joining an intellectually stimulating, socially responsible company with a track record of addressing serious illnesses and public health issues around the world. Our employees include some of the most talented innovators in the biopharmaceutical industry. Through our ongoing bold and transformative science, we’re driving innovations that have the potential to become the next generation of life-changing medicines. We have commercialized more than 25 innovative medicines, helping to transform treatment for people living with HIV, viral hepatitis, cancer and other life-threatening diseases. This role will be hybrid based out of our Philadelphia or New Hope, PA office.Gilead has pursued and achieved breakthroughs in medicine for more than three decades, with the goal of creating a better, healthier world for all people. AdMed has over 30 years of industry experience and we are looking for a dynamic, passionate, experienced Assistant Medical Writer to join our team. This is tomorrow’s teaching like you’ve imagined it – with proven results. AdMed is an award winning, integrated agency that designs and delivers modern training tools for pharmaceutical, biotech, diagnostic and medical products, with one goal: to ensure that healthcare professionals, sales teams, employees and consumers understand what they need to know regarding the science behind their products.
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Tell your doctor if you or your child have or had depression or have tried to harm yourself or themselves. Mental health problems, including confusion, seeing or hearing things that are not real (hallucinations), unusual or disturbing thoughts (abnormal thinking), feeling anxious or upset, depression, thoughts of killing yourself or trying to kill yourself, increased tiredness, feelings of guilt or worthlessness, and difficulty concentrating.People who already have breathing or lung problems have a higher chance of having breathing problems when they take XYREM. Breathing problems, including slower breathing, trouble breathing, and/or short periods of not breathing while sleeping (sleep apnea).XYREM can cause serious side effects, including the following: Those activities should not be done until you know how XYREM affects you or your child.įalling asleep quickly, including while standing or while getting up from the bed, has led to falls with injuries that have required some people to be hospitalized. Tell your doctor if you have ever abused or been dependent on alcohol, prescription medicines, or street drugs.Īnyone who takes XYREM should not do anything that requires them to be fully awake or is dangerous, including driving a car, using heavy machinery, or flying an airplane, for at least 6 hours after taking XYREM. Selling or giving away XYREM may harm others, and is against the law. Keep XYREM in a safe place to prevent abuse and misuse. You or your child must be enrolled in the XYWAV and XYREM REMS to receive XYREM.ĭo not take XYREM if you take or your child takes other sleep medicines or sedatives (medicines that cause sleepiness), drink alcohol, or have a rare problem called succinic semialdehyde dehydrogenase deficiency. Call your doctor right away if you or your child has any of these serious side effects.īecause of these risks, you have to go through the XYWAV and XYREM REMS. These effects include seizures, trouble breathing (respiratory depression), changes in alertness (drowsiness), coma, and death. Abuse or misuse of illegal GHB alone or with other CNS depressants (drugs that cause changes in alertness or consciousness) have caused serious side effects. The active ingredient of XYREM is a form of gamma hydroxybutyrate (GHB). WARNING: Taking XYREM with other Central Nervous System (CNS) depressants such as medicines used to make you or your child fall asleep, including opioid analgesics, benzodiazepines, sedating antidepressants, antipsychotics, sedating anti-epileptic medicines, general anesthetics, muscle relaxants, alcohol, or street drugs, may cause serious medical problems, including trouble breathing (respiratory depression), low blood pressure (hypotension), changes in alertness (drowsiness), fainting (syncope), and death. The carrier bag has an opening at the lower side for the snout of the canister to protrude outside the bag, so it can be quickly hooked to the vehicle GPFU without removing it. The top flap is closed with three LTD fasteners or with a velcro strip. The carrier bag allows the M25 mask to be slung over a shoulder or carried around the waist for rapid access in the case of NBC attack. When wearing the M25 mask for stand-alone protection, the wearer inhales air through the M10A1 canister at the end of the hose. This increases protection while reducing heat stress in hot weather. The GPFU forces filtered temperature- controlled air to the facepiece. When the M25 mask is used in a vehicle, the canister snout attaches to a filter unit, such as the M13A1 gas-particulate filter unit (GPFU). Filter canisters for the M24 and M25 masks are interchangeable - both use the M10A1 CB canister (NSN 4240-0). The Mask Chemical-Biological Tank ABC-M25 is almost identical to the Mask, Chemical-Biological Aircraft, ABC-M24 except for the microphone. If both are available for comparison, the M25A1 will be seen to have a higher forehead tab. The M25 Tank Gas Mask and the M25A1 mask are visually almost identical. Only the prong-type of optical insert fits M25A1 gas mask As issued, the M25 Tank Gas Mask, carrier, and accessories are sealed together in a single foil package. The M25 tank gas mask as issued consists of a wide view, clear plastic lens embedded in a butyl rubber face blank, an integral microphone with cord and coupler plug, eye lens outserts, heavy cotton duck carrying case, anti-fog kit, and an olive drab hose with mounted filter canister. The M25A1 was produced until 1988 and remained in use into the 1990s, ultimately replaced by the M42 Combat Vehicle Gas Mask. Almost immediately, the M25A1 was adopted with minor changes and improvements including eye-lens outserts for arctic use and better fit. The M25 Tank Gas Mask, approved for use in 1962 and fielded in 1963, is essentially identical to the M14A2 Tank Mask but with the addition of a new microphone system, the M116G used with the AN/VRC-12-series radios. The image would be generated from the data supplied by on-board video camera located in the front and the rear of the aircraft.Įxample : When the aircraft is taxiing on the ramp, the screen would display a 3D image of the airport generated from the data captured from the video camera and the data stored in data banks on ground. The digital image would be projected in the form of a hologram or any other advance technology. Airbus also claims that this invention can increase the payload capacity of the aircraft in their patent. This not only gives a better aerodynamic design to the aircraft, but also increases the pilots’ field of view. Since there is no need for the pilot to actually look outside, the entire cockpit can be shifted to another location freeing up space in the front of the fuselage. This invention solves this problem by shifting the cockpit at another location which allows the engineers to modify the shape of the nose. Conventionally, it is located in the front of the fuselage with slanted window panes which allows the pilots to have an unobstructed view of both forward and downward of the aircraft.įor maximum aerodynamic efficient design, the nose of the aircraft should ideally be of lancet shaped (like a knife) but to accommodate the radome and the landing gear, it is modified to give a larger radius of curvature. The cockpit is the room reserved for pilots comprising of all controls necessary to fly the aircraft. Looking at the bigger picture, this invention is basically replacing the glazed cockpit window with a large screen displaying a digital image of the outside environment. In 2014, Airbus registered a patent featuring the idea of “windowless” cockpit which would increase pilots’ field of view. This may look stupid to many of the readers, but Airbus advocates that it may be the future of aircraft design. You would feel dumbfounded be reluctant to board the aircraft, right? Well, in a few years you may find every Airbus aircraft without cockpit windows. This exhibit brings together passenger ephemera and other materials from the collections of Northwestern University’s Transportation Library to celebrate the jumbo jet on the fiftieth anniversary of the launch of 747 passenger service.Imagine that you are boarding an aircraft and you find out that there are no cockpit windows, rather an opaque cone of metal sheet covering the entire cockpit window area. The jumbo jet came to occupy a permanent place in the popular imagination around the world and remains, decades later, a symbol that represents the glamour of air travel in a bygone age. Spacious interiors with luxury appointments and enhanced in-flight dining and entertainment experiences, available to first-class and economy passengers alike, served as marketing tools for the airlines that operated the 747. With increased capacity and lowered costs, the 747 helped make the air travel experience accessible to middle-class travelers. With the first flight from New York to London, Pan Am’s Clipper Young America ushered in the jet age’s second phase: the era of wide body aircraft.ĭeveloped by Boeing to maximize seat-mile and ton-mile revenues, the aircraft also extended the golden age of air travel as the 1960s came to a close. Longer than the Wright brothers’ first flight, wider than a boulevard, and with a tail height as tall as a six-story building, the 747 was a revolution in aviation technology and the passenger experience when it entered service on January 22, 1970. By using high-contrast black-and-white film to create the mattes, you can create the silhouettes. These mattes are easy to create because the bright blue color, when run through a red filter, turns black. One shows the actress's silhouette in black, and the other is the reverse, like this: In the special effects department you can easily use special filters to form two mattes from the shot of the actress. You end up with two pieces of film that look like this:įilm of the river gorge, known as a "plate" Behind the actress in the studio you place a bright blue background screen (hence the name "blue screen"). You then film the actress dangling from a rope 2 feet off the ground in a studio. This shot is called the background plate. To use the blue screen technique, you first film the river gorge on location. Perhaps the clouds are filmed with a slow film speed, so that when played at normal speed they look like they are boiling across the sky. Then, the camera operator rewinds the film in the camera, puts a piece of black paper on the lens to mask out the portion of the film already exposed, and films the clouds of a thunderstorm. The scene is shot normally, but in the camera the film is exposed on only one half of the frame. When this shot is created, however, a piece of black paper or tape is used on the lens so that the area of the sky is masked out and left unexposed on the film. To create this effect, the cameraman can first shoot the actors on the plain. Let's say that the director would like to create a spooky scene where the actors are walking across a large, flat plain while the sky boils with dark clouds. A very common effect can be easily created using a double-exposure matte. Mattes have been used in the film industry practically forever to create special effects. The original scene: Actors on a plain on a nice day Not very spooky. I was going to keep listing out mods but there are actually hundreds so instead look through this search on modthesims to find all mods that make things faster. Mods that speed up the interactions in the game - Quick Shower & Quick Bath and Random Small Mods (Faster Run To University Class, Higher Skill Faster Candle Making, Restaurant Faster Cooking) by LittleMsSam Homework Tweaks, Faster Homework (University Edition), Faster Retail Actions and Faster Brewing by Scarlet.You only need one version of the mod, but Coolspear advises you to test each to find the one that works best for you. Place the override folder into your mods folder and extract the mod into it. To use Coolspear's mod you'll also want to download this override folder. If you change the time speed with MCCC as described above you have to use Coolspear's mod as SrslySim's doesn't support that. rar file) and SrslySims' Simulation Lag Fix. There are two main simulation lag mods to try, Coolspear's Quicker Sim Autonomy and Simulation Lag Fix (you'll have to create an account and scroll down to the part that says 'Quicker Sim Autonomy' and open the spoiler to find the. Simulation Lag Fixes - simulation lag isn't necessarily the problem you're having (you'll definitely know when you are - sims will stand around doing nothing for hours or will start walking through walls and objects when trying to route to places quicker), but I thought I'd cover it since other people mentioned it.I use 50 which makes days take double the time they would be by default. Input a number greater than 25 to slow down the speed of the day. To find this setting, click on a computer > MCCC > MCCC Settings > Gameplay Settings > Game Time Speed. So for example, if it takes 2.5 in-game hours to eat a ham and cheese sandwich on normal settings, changing the time speed to be slower by half will make it so that it still takes the same time to carry out the animation in real time but only takes 1.25 in-game hours. MC Command Center - In MCCC you can change the games time speed to be faster or slower than default, meaning that the in-game time will be faster or slower in real time.Depends on personal taste, so you might want to try a few of these to see what works for you. There are tons of mods that can make things quicker, or make the time spent in-game hours more appropriate. Regardless, that wasn't even the point I was trying to make. Nope Ultrons blast shoot through the entire length of a train and burned through ever wall in its path Cap took twice that to the chest. For about three seconds There's no comparison to be made in any of the GIFs you put up, you're delusional if you believe so. Steve got hit with a grenade launcher he blocked with his shield, which sent him flying and then flying into a bus through its window. Chitauri are not quite as strong as Cap from their physical struggles seen throughout the battle. while Tony is grunting and struggling to his feet he get shot down by a Chitauri next time we see him a group of Chitauri are hitting him down with physical attacks with him grunting in pain upon every hit. He don't know that they have ant man, hawkeye or scarlet witch or think that only hawkeye will Lol what, Iron Man easily tanked that explosion which sent him flying to the ground he hit a car that didn't even seem to get damaged in which he stood back up without any real damage. The reason he use this despite having the time to go back in NY and grab something better is he think that this is enough to deal with 2 super soldier and Falcon. Maybe the suit is the bigger version of that, trade power and durability for quick access so that he can suit up anytime he like and then stall for more powerful armor to come. Power: remember the gauntlet from watch. This mean it can survive in water for an hours but not suited for long underwater combat. Water/Ant man proof: most say that ant man can go smaller that water droplets but here is my other reason: the suit has mechanic that close the gap when contact with water. WTF logic do you think someone like Tony will build something for someone else that he can't outspeed/damage? The durability feats is also flying through chitauri ship and tank explosion. Tony build the wing for Falcon in Civil war and then couldn't catch up to him. 19, 2022, in “The Astrophysical Journal Letters. The discoverers: A team led by Shreyas Vissapragada of the Center for Astrophysics Harvard & Smithsonian published the new study of Kepler-1658 b on Dec. A year on Kepler-1658 b, once around the star, takes just under four days. They are gas giants, like our own Jupiter, but in extremely tight orbits around their stars – a “year” on these planets, in fact, typically lasts less than 10 days. 30 Rock (2006) - S02E13 Succession clip with quote Cause rumor has it that hes trying to pull a death spiral, Yarn is the best search for video clips by. Kepler-1658 b also appears to be brighter and hotter than scientists expected, another possible result of tidal interaction with the star.įun facts: Hot Jupiters, although among the first exoplanets to be discovered, are strange worlds unlike any in our solar system. Our home planet also could meet its end when the Sun grows so large it might swallow Earth, billions of years from now. That expansion increases the gravitational interaction between the star and the planet the star, in a sense, robs the planet’s orbit of its energy. In aviation, a graveyard spiral is a type of dangerous spiral dive entered into accidentally by a pilot who is not trained or not proficient in flying in instrument meteorological conditions (IMC). The team also showed that the giant planet’s decaying orbit is best explained by tidal forces from its parent star, which, as it moves toward its end stage, is expanding. By measuring subtle shifts in the timing of Kepler 1658 b’s transits across the face of its swollen star, a study team determined the planet was arriving earlier than its expected transit times – a key piece of evidence that the planet’s orbit is shrinking. And these techniques continue to grow in refinement. Astronomers Discover Planets in NASA Kepler's Final Days of Observationsĭetails: Exoplanet scientists deploy an array of techniques to study distant planets, from the “transit” method Kepler used to discover Kepler-1658 b – measuring the tiny dip in starlight as the planet crosses in front of its star – to carefully tracking the wobbles of parent stars, revealing the gravitational tugs of unseen planets. You can upload your video to YouTube and share to Facebook, Twitter, and Google+ at the same time. Film a video and instantly make it YouTube-ready with background music, auto color correction, and auto stabilization. Using the screen recording feature on iOS (iPad or. You can upload your video to YouTube and share to Facebook, Twitter, and Google+ at the same time. Rather than subscribing to YouTube Premium, heres a quick and easy way for you to save a file of a part of a video.or even an entire video. It has a lot of the editing features that the website version also includes, but YouTube Capture is not a substitute for a full functioning video recording and uploading program. Record Video with an External Mic and Power Source on Your iPhoneThe nonexistent headphone jack on the newer iPhones can be an annoyance. YouTube Capture is a great, simple video recorder and uploader for YouTube. Read on to record Youtube videos and edit them to perfect the video. The iPhone 14 Pro cinemaitc video settings can shoot some amazing video, however there are some features are disabled by default so in order take full advant. You do not have the same amount of options as a full-fledged video editor, but if you want to share videos quickly with friends, YouTube Capture is a great option. Full Guide How to Record YouTube Videos on PC/Mac/iPhone/Android/Online - EaseUS How to record YouTube videos on different platforms with simple clicks Here you can learn how to record Youtube videos on a Windows PC, a Mac, an iPhone, an android, and online with a full guide. The enhancements in YouTube Capture have options for color correction, stabilization, trimming the video, and adding different stock soundtracks. After you finish recording, you can enter a title, share the video to different social networks, and enhance the video. This camera app gives you control over your exposure, flash, focus, ISO, shutter speed, torch, and white balance. If youd like to maintain a certain level of control over how your videos are edited and want to remove them from your phone after shooting, treating your. By default, when you rotate the device into landscape mode, the app will start recording. In this tutorial, you have learned how to use the SQL Server ALTER TABLE DROP COLUMN statement to remove one or more columns from a table. The following example deletes two columns discount and surcharge at once: ALTER TABLE sales.price_lists To drop the price column, first, delete its CHECK constraint: ALTER TABLE sales.price_listsĪnd then, delete the price column: ALTER TABLE sales.price_lists Here is the error message: The object 'ck_positive_price' is dependent on column 'price'. I would like to perform this operation with as little as possible down-time. If you try to execute the following statement, you will get an error: ALTER TABLE sales.price_lists How to delete a column from a MySQL big table Ask Question Asked 10 years, 9 months ago Modified 10 years, 9 months ago Viewed 875 times Part of PHP Collective 3 I have a 250GB 500M rows MySQL table and would like to delete one of its columns. The price column has a CHECK constraint, therefore, you cannot delete it. The following statement drops the note column from the price_lists table: ALTER TABLE sales.price_lists Price DEC( 10, 2) NOT NULL CONSTRAINT ck_positive_price CHECK(price >= 0), Letâs create a new table named sales.price_lists for the demonstration. SQL Server ALTER TABLE DROP COLUMN examples In this syntax, you specify columns that you want to drop as a list of comma-separated columns in the DROP COLUMN clause. If you want to delete multiple columns at once, you use the following syntax: ALTER TABLE table_nameÄROP COLUMN column_name_1, column_name_2. Also, SQL Server does not allow you to delete a column that has a PRIMARY KEY or a FOREIGN KEY constraint. If the column that you want to delete has a CHECK constraint, you must delete the constraint first before removing the column. Allowed value types are listed in mysqlxdatatypet enum. The list should be terminated using PARAMEND. list of column-value specifications consisting of triplets.Second, specify the name of the column that you want to delete. table: table handle : criteria: expression selecting rows to be updated (WHERE clause).First, specify the name of the table from which you want to delete the column.Asking for help, clarification, or responding to other answers. To do this, you use the ALTER TABLE DROP COLUMN statement as follows: ALTER TABLE table_nameĬode language: SQL (Structured Query Language) ( sql ) It is possible to delete all rows in a table without deleting the table. Thanks for contributing an answer to Stack Overflow Please be sure to answer the question.Provide details and share your research But avoid. Sometimes, you need to remove one or more unused or obsolete columns from a table. Introduction to SQL Server ALTER TABLE DROP COLUMN If you don't need it to check for NULL then you can remove that part.Summary: in this tutorial, you will learn how to use the SQL Server ALTER TABLE DROP column statement to remove one or more columns from existing table. My function will check for a whole row of empty columns or NULL columns at the same time. Introduction to SQL DROP COLUMN statement tablename is the name of the table which contains the columns that you are removing. You just need to send in a different table name and array and it will work. To remove an existing index from a table, you use the DROP INDEX statement as follows: DROP INDEX indexname ON tablename algorithmoption lockoption Code language: SQL (Structured Query Language) (sql) In this syntax: First, specify the name of the index which you want to remove after the DROP INDEX keywords. You can use this function for multiple tables. $this->deleteBlankLines("tableName",$tableArray) Īnd here is the function which takes the array and builds the delete string private function deleteBlankLines($tablename,$columnArray)` WHERE ".$Where $tableArray=array("Address", "Email", "Phone") //This is the column names I call my function with an array so that I can use the same function for different tables. I know this has already been answered and has got a tick, but I wrote a small function for doing this, and thought it might be useful to other people. |
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